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whiskey in the jar
Indoor spraying of a compound called bendiocarb may provide a backup now that malaria mosquitoes are becoming resistant to mainstay insecticides, a large study in Benin suggests. But scientists say more alternatives are urgently needed-if only because of bendiocarb's toxicity.
Bendiocarb is a candidate replacement for pyrethroids, compounds whose wide-spread use in indoor spraying and bednets is causing resistance in Anopheles mos-quitoes, the vector for malaria, especially in West Africa. After government teams carried out two rounds of spraying in 2008 and 2009 in an area in Benin where 350,000 people live, Anopheles bites fell by more han 90%, and traps didn't yield a single infected mosquito, researchers reported last week in The American Journal of Tropical Medicine and Hygiene.
Bendiocarb is a candidate replacement for pyrethroids, compounds whose wide-spread use in indoor spraying and bednets is causing resistance in Anopheles mos-quitoes, the vector for malaria, especially in West Africa. After government teams carried out two rounds of spraying in 2008 and 2009 in an area in Benin where 350,000 people live, Anopheles bites fell by more han 90%, and traps didn't yield a single infected mosquito, researchers reported last week in The American Journal of Tropical Medicine and Hygiene.
Bendiocarb, which inhibits a brain enzyme called acetylcholinesterase, is among a dozen insecticides approved by the World Health Organization for malaria control, but safety concerns led manufacturers
to voluntarily withdraw it from the U.S. mar-ket in 1999. Beninese teams did not spray in low-lying areas prone to flooding, where they feared toxic run-off into local waters.
to voluntarily withdraw it from the U.S. mar-ket in 1999. Beninese teams did not spray in low-lying areas prone to flooding, where they feared toxic run-off into local waters.
SOURCE : SCIENCE MAGAZINE VOL 334
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